Some Relations between Chemical Structure and Antifungal Effects of Griseofulvin Analogues.

نویسندگان

  • R CROSSE
  • R MCWILLIAM
  • A RHODES
چکیده

Inhibitory effects of more than 300 analogues of griseofulvin against six dermatophytic fungi and eight plant pathogenic fungi were determined in an investigation of relations between chemical structure and biological activity. The influence of chemical structure on physical properties of the analogues appeared dominant, but optimum requirements for in vitro performance were somewhat different from those required in vivo for effective control of plant pathogenic or dermatophytic fungi.

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عنوان ژورنال:
  • Journal of general microbiology

دوره 34  شماره 

صفحات  -

تاریخ انتشار 1964